24.11.2022
Woman, 33, given 1 year to live after spotting change in bowel movement while on vacation

Bowel cancer starts off as a group of benign cells called polyps. Their malignancy tends to develop over the course of about 10 to 15 years, producing increasingly noticeable symptoms along the way. One case study highlights the possibility of symptoms emerging only in the advanced stages of bowel cancer when the condition cannot be reversed.

The patient’s doctor, David Liu, told Cure Today: “She was a 33-year-old woman presenting with bowel obstruction while on vacation with her one-month-old baby.

“On diagnosis, she had stage 4 metastatic colorectal carcinoma […]. She came with a unique perspective, which was wanting to do anything and everything to spend as much time as possible with her family.”

This led doctors to treat her off protocol despite her “estimated survival of approximately one year”.

After careful consideration of the patient’s presentation, the doctors proceeded to treat her liver, which improved her chances of living longer.

“The patient later developed ovarian drop metastases, which were surgically resected. She also developed pulmonary lesions, which were effectively treated with a combination of ablation and surgical resection.

“In the end, she developed brain metastases,” which eventually led to her death.

The end of the report states that the patient survives 54 months, “which is significantly longer than the 12-month anticipation”.

There is a widely held belief that bowel movements are impossible during bowel obstruction, but some people do pass stool.

Their symptoms are typically pain, bloating and nausea, and they may even have stool stools during bowel obstruction.

In colon cancer, bowel obstruction is suggestive of narrowing of the bowel, which prevents stool from passing.

Other cancers, however, such as lung and breast cancers can also spread to the abdomen and cause bowel obstruction.

Life expectancy is lower in stage 4 cancer than it is in the earlier stages of the disease.

The five-year relative survival rate for stage 4 bowel cancer that has metastasised and spread to neighbouring tissue is about 14 percent.

This makes it difficult to remove cancer completely, but treatment can still prolong survival and improve quality of life.

At this final stage of the disease, symptoms are bound to be most noticeable, making them hard to ignore.

The Cancer Centre explains: “Stage 4 colorectal cancer has spread beyond the [bowel] or rectum to distant areas of the body, including tissues and/or organs.”

The health body adds that the disease is marked by the following specific characteristics:

“Stage 4A: The cancer has reached one area or organ that isn’t near the colon or rectum (such as the liver, lung, ovary or faraway lymph node).

“Stage 4B: The cancer has reached more than one area or organ that isn’t near the colon or rectum.

“Stage 4C: The cancer has spread to distant parts of the tissue that lines the abdominal wall and may have reached other areas organs.”

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  • 1 час, 7 минут назад 01.12.2022Health Care
    Two toilet symptoms that may signal a deadly blood clot has formed in a ‘major vein’

    The most common place for blood clots to form is in the lower leg due to decelerating blood flow to the lower limbs. Sometimes, however, a blood clot may form in the veins leading to the stomach. This potentially life-threatening complication could produce specific signs when going to the toilet.

    The splenic, superior or inferior mesenteric veins all deliver nutrient-rich blood to the liver through the hepatic portal vein.

    When a blood clot forms in these veins it prevents blood flow to the intestines, which can lead to the damage or death of tissue in this organ.

    Blood clots that form in the stomach or abdominal area are medically recognised as a type of deep vein thrombosis called mesenteric venous thrombosis (MVT).

    MedlinePlus defines MVT as a “blood clot in one or more of the major veins that drain blood from the intestine”.

    Ignoring these symptoms could be dangerous, as delayed treatment of the condition can result in life-threatening intestinal infarction.

    Unfortunately, however, the condition is not easy to diagnose.

    The most common symptom to arouse concern in patients is acute abdominal pain, but many cases develop asymptomatically.

    This discomfort, often described as dull pain around the navel area, is a sign that blood flow in the intestine is starting to falter.

    The pain caused by blood clots in the bowel comes on quickly but sometimes develops slowly over the course of weeks or months.

    Another important characteristic of this pain is that it won’t intensify when a doctor pushes on the abdominal area, as pain from appendicitis or diverticulitis would.

    Moreover, it tends to be more pronounced after eating a meal, according to Medline Plus.

    While the exact causes for these thrombotic events are unknown, many potential triggers have been identified.

    The risk factors for MVT are generally the same as those for deep vein thromboses, such as surgery and sedentary behaviour.

    Additional risk factors, however, may include digestive ailments that trigger swelling of the tissues surrounding the intestines.

    For example, injury to the abdominal area, inflammatory bowel disease or cancers of the digestive system, could all lead to clotting events.

    People who use hormone therapies or use contraceptive medication like birth control pills could also be at a heightened risk for such complications.

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  • 1 час, 7 минут назад 01.12.2022Health Care
    Do you feel groggy? Research shares 3 simple tips that are key to waking up refreshed

    From a midday slump to tough mornings, sometimes there’s not enough coffee in the house to keep you going. However, if you struggle to wake up refreshed regularly, you might want to switch things up. New research suggests that the secret to waking up alert could be as simple as three lifestyle tweaks.

    If you don’t want to see or speak to anyone before you’ve had your first cup of coffee, you’re not alone.

    Many people are foreign to the concept of morning alertness but a new study, published in the journal Nature Communications, suggests that waking up refreshed each day is not just something a lucky few are born with.

    Scientists at the University of California, Berkeley, found that morning grogginess could be easily tackled by three key factors: sleep, exercise and breakfast.

    These findings come from a detailed analysis of the behaviour of 833 people who had to eat a variety of breakfasts, wear wristwatches to record their sleep quantity and physical activity, as well as keep a food diary.

    The research team found that morning alertness can be achieved by a three-part prescription.

    All you need to do is exercise the previous day, sleep longer and later into the morning, and eat a special breakfast.

    Your first meal should be high in complex carbohydrates and limit sugar because a healthy controlled blood glucose response after breakfast is key to waking up more effectively.

    Raphael Vallat, the first author of the study, said: “All of these have a unique and independent effect.

    “If you sleep longer or later, you’re going to see an increase in your alertness.

    “If you do more physical activity on the day before, you’re going to see an increase. You can see improvements with each and every one of these factors.”

    The study subjects were given pre-prepared meals that consisted of muffins packed with different amounts of nutrients.

    A standardised breakfast of moderate amounts of fat and carbohydrates was compared to high-protein option (muffins plus a milkshake), and a high-carbohydrate or high-sugar breakfast (glucose drink).

    The worst type of breakfast turned out to be the meal that contained high amounts of simple sugar, which resulted in an inability to wake up effectively and maintain alertness.

    In contrast, the high-carbohydrate breakfast, and only a modest amount of protein, were linked to individuals revving up their alertness quickly in the morning.

    “A breakfast rich in carbohydrates can increase alertness, so long as your body is healthy and capable of efficiently disposing of the glucose from that meal, preventing a sustained spike in blood sugar that otherwise blunts your brain’s alertness,” Vallat said.

    However, it’s not all about food as sleep also matters significantly for your morning alertness.

    According to senior author Matthew Walker, between seven and nine hours of sleep is ideal for ridding the body of “sleep inertia”, which details the inability to transition effectively to a state of functional cognitive alertness upon awakening.

    Most people need this amount of sleep to remove a chemical called adenosine that accumulates in the body throughout the day and brings on sleepiness in the evening.

    “Considering that the majority of individuals in society are not getting enough sleep during the week, sleeping longer on a given day can help clear some of the adenosine sleepiness debt they are carrying,” Walker said.

    While it’s unclear how physical activity improves alertness the next day, exercise was proven to improve grogginess and mood levels in their research.

    This makes these three interventions a “relatively simple prescription for how best to wake up each day”.

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  • 1 час, 7 минут назад 01.12.2022Health Care
    ‘A child died last week’: Deadly and contagious virus is circulating – symptoms

    The Year One pupil from Ashford Church of England School, Kent, died last week after battling a Group A streptococcal (iGAS) infection. One local parent said: “Parents are of course getting very concerned about this outbreak, especially as a child died last week. “It is every parent’s worst nightmare. We are being told to keep sending our kids into school…

    “But it feels incredibly risky given there are now at least four cases in the local area at two different schools.”

    Group A streptococcal infections are caused by bacteria that “colonise the throat, skin and anogenital tract”, the NHS says.

    “It causes a diverse range of skin, soft tissue and respiratory tract infections,” the health body adds.

    The Streptococcus pyogenes bacteria can lead to:

    Post-streptococcal complications can include: rheumatic fever and glomerulonephritis.

    The bacteria “can occasionally cause infections that are extremely severe”.

    Invasive Group A Streptococcus (iGAS) “is an infection where the bacteria are isolated from a normally sterile body site, such as the blood”.

    The bacteria can spread by close contact between individuals, through respiratory droplets and direct skin contact.

    “It can also be transmitted environmentally, through contact with contaminated objects, such as towels or bedding or ingestion of food inoculated by a carrier,” the NHS notes.

    Dr Claire Winslade, health protection consultant at UKHSA South East, commented on the outbreak.

    “We are extremely saddened to hear about the death of a pupil at Ashford Church of England School,” said Dr Winslade.

    “And our thoughts are with their family, friends and the school community.

    “As a precautionary measure, we have recommended antibiotics to pupils and staff in the same year groups as the individuals affected.

    “We have provided advice to the school to help prevent further cases and will continue to monitor the situation.”

    The symptoms of iGAS, said Dr Winslade, include:

    “Anyone with these symptoms should call NHS111 immediately,” Dr Winslade advised.

    Dr Winslade continued: “Infection with Group A Streptococcus bacterium usually causes a sore throat or skin rash.

    “In very rare cases, the infection can become invasive and enter parts of the body where bacteria aren’t normally found, which can be serious.”

    Common signs and symptoms of Scarlett fever, according to the Centres for Disease Control and Prevention (CDC), include:

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  • 3 часа, 7 минут назад 01.12.2022Health Care
    Troubled teacher drove wrong way down M4 at high speed

    A teacher who died after deliberately driving the wrong way down an M4 slip road had been diagnosed with bipolar disorder, an inquest has heard.

    Lewis John Hunter Gilmour, 37, had sent several texts indicating that he wanted to die in the hours before his car crashed with an oncoming vehicle.

    The conclusion of the inquest into his death, which first opened in 2018, was held at Swansea Coroner’s Court on Wednesday, November 30 2022. The inquest had been adjourned to allow for a clinical incident report to be put to the court, WalesOnline reports.

    Mr Gilmour had been diagnosed with bipolar disorder in 2011 and his mental health had started to deteriorate in September 2017. In June 2018, shortly before his death, he contacted mental health services after attempting suicide.

    On June 29, he contacted his former partner Jane Ballantyne, with whom he’d been in a relationship for nine months which ended in early 2018. Mr Gilmour’s mental health issues had started to have an impact on the relationship before it ended, but the two had stayed friends. Ms Ballantyne had become “extremely concerned” for Mr Gilmour’s welfare and received a series of messages from him including one at 11.01pm on July 1 in which he said: “I just want to die.” Ms Ballantyne then called him at 11.56pm and he didn’t pick up, so she called the police.

    Mr Gilmour sent more messages shortly before driving his car at a high speed the wrong way down a slip road near junction 47 on the M4 into another car.

    Forensic investigations found no sign that Mr Gilmour had taken evasive action. Christopher Gordon, driver of the other car – a Vauxhall Astra – suffered serious injuries. Mr Gordon previously told the inquest that he had swerved to avoid Mr Gilmour’s car, something which the investigators found no evidence either for or against.

    Mr Gilmour died at the scene as a result of multiple injuries due to the road traffic collision. A toxicology report found there was no evidence of alcohol or substance abuse by Mr Gilmour, and that he had a “therapeutic level” of lithium in his system which was part of his medication for bipolar disorder.

    The acting senior coroner, Mr Colin Phillips, recorded a conclusion of suicide. For this, he had to be satisfied that Mr Gilmour carried out actions resulting in his death, and that he intended for them to result in his death.

    Mr Phillips said that Mr Gilmour’s actions were “of a man suffering a mental health crisis.” He continued: “He had recently attempted suicide and told Ms Ballantyne that he just wanted to die.”

    The coroner added: “The risk of self-harm had not been appreciated by those responsible for his healthcare.”

    Shortly after Mr Gilmour’s death, the 37-year-old’s family released a statement: “We, Lewis’ family and all of his friends have been shocked and devastated by his tragic and untimely death.

    “Many have already spoken of a lovely guy whose kindness, generosity of spirit, unfailing sensitivity to the needs of others, combined with a wicked sense of humour, served to make him unforgettable.”

    For confidential support the Samaritans can be contacted for free around the clock 365 days a year on 116 123.

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  • 3 часа, 7 минут назад 01.12.2022Health Care
    ‘Quick’ exercises you can do at your desk to prevent blood clots forming – expert

    Blood clots are tiny clumps of blood that become gel-like. Although the ability to create clots is necessary as it stops excessive bleeding, they can become a problem. If clots don’t dissolve naturally they can be dangerous.

    This is because they can travel to vital organs in the body, causing potentially fatal medical emergencies.

    Examples of this include pulmonary embolisms, when the clot travels to the lungs, and ischaemic strokes, when the clot blocks blood and oxygen supply to the brain.

    There are a number of factors that can increase your likelihood of developing blood clots.

    One such factor is not exercising enough.

    Co-founder of Volonté, Haylene Ryan-Causer, spoke with Express.co.uk to explain more.

    The fitness expert, sprinter and Olympic weightlifter recommended ways to prevent clots forming if you have a sedentary job.

    She said: ”Keeping good blood circulation throughout the day can help reduce the risk of clots forming as well.

    “Since most people spend most hours of their day at a desk, it is important to do quick exercise such as ankle rotations, pointing and flexing their feet, knee lifts to the chest, shoulder rotations and light five to 10 minute walk every two hours would help keep circulation going.

    “In a larger spectrum of exercise, cardio workouts such as walking, biking and rowing regularly three to four times a week can help cardiovascular blood circulation and health which can reduce the risk of clot formation.”

    According to the NHS, other ways to prevent the risk of blood clots include:

    Ms Ryan-Causer’s colleague and co-founder of Volonté, Vidushi Biani, shared some of the best foods to eat to further prevent your chances of a clot.

    The nutrition expert added: “The best way in my opinion to have a clean diet, is not by restricting food groups, but rather to avoid eating highly processed and fatty foods.

    “Try and eat more home cooked meals to avoid consuming excess sodium, sugar and fat.

    “Avoid consuming excessive amounts of caffeine if you spend most of your day at a desk, as caffeine increases cortisol levels, which if not used up, can lead to increased fat storage in our bodies.

    “Eat a balanced diet that includes plenty of vegetables, wholegrains, lean proteins, and omega rich fats.”

    Deep vein thrombosis (DVT) is a condition that occurs when a clot forms in the arm or leg.

    DVT is particularly dangerous as the blood clot can break loose and travel to the lungs, causing a pulmonary embolism.

    Signs of DVT to look out for include:

    Signs that a clot has reached the lungs are:

    If you experience chest pain or breathlessness the NHS advises seeking medical help immediately.

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  • 3 часа, 7 минут назад 01.12.2022Health Care
    Covid ‘may lead to liver injury that lasts well after acute illness’, suggests study

    According to a study published at the annual meeting of the Radiology Society of North America acute, that is to say severe, illness resulting from COVID-19 could result in damage to the liver.

    Specifically, it could result in a liver injury, this is when trauma is sustained to the liver. Another way to put it is that if someone’s foot was crushed they would sustain an acute foot injury.

    Research fellow at the Massachusetts General Hospital where the research was carried out Doctor Firouzeh Heidari said: “Our study is part of emerging evidence that COVID-19 infection may lead to liver injury that lasts well after the acute illness.”

    COVID-19 was also found to cause liver stiffness, another marker of liver damage; liver stiffness can indicate inflammation or fibrosis of the organ and cause long term damage.

    Such long-term damage involves the healthy liver tissue diminishing and a subsequent loss of function of the liver.

    Furthermore, progressive fibrosis, also known as liver scarring, can potentially lead to liver cancer too.

    It is for this reason that the researchers are concerned about the impact of COVID-19 on the liver.

    The researchers in question conducted a retrospective study, one where they compared liver stiffness of patients with and without a history of a COVID-19 infection.

    When the results were collected, and after controlling for age, sex, and time period, it was found those with a history of a Covid infection had much higher liver stiffness than those who didn’t.

    However, what was unusual was the pre-pandemic control group, measured from a time when Covid wasn’t circulating, had a higher level of stiffness than those who weren’t infected with Covid during the pandemic.

    As to why this was the case, the scientists couldn’t ascertain. What it doesn’t take away from was the impact of Covid on the livers of patients.

    Despite the warnings, Doctor Heidari was keen to point out that this was an early stage study and that there were multiple unknowns still to be deciphered.

    Doctor Heidari wrote: “We don’t yet know if elevated liver stiffness observed after COVID-19 infection will lead to adverse patient outcomes.

    “We are currently investigating whether the severity of acute COVID-related symptoms is predictive of long-term liver injury severity.

    “We hope to enrich our existing database with additional patient data and a broader scope of co-variates to better understand the post-acute effects of COVID-19 within the liver.”

    As a result, further studies are needed to ascertain the long term impact of COVID-19 on the liver; but what it does reveal is another way in which the virus affects the body; something already being seen with long Covid.

    Long Covid currently affects around two million people in the UK. A chronic condition, it causes a range of symptoms and people of all ages.

    This includes children, a group which make up a small part of the long Covid data, but a group for whom some argue long Covid is even more significant if new treatments aren’t developed.

    To this end, charities such as Long Covid Kids have been founded.

    Their aim is to raise awareness of long Covid in children and to campaign for new treatments so that their illness does not haunt them into their adulthood.

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Health Care Woman, 33, given 1 year to live after spotting change in bowel movement while on vacation